We’ve been following director Vincenzo Natali’s latest film Splice for a little while now because, among other reasons, we’re big fans of sci-fi around here and his first film, Cube, was a pretty great low-budget first feature effort. And now, thanks to the power of the Internets (and the folks at Collider), we can bring you a new clip from the film as well as a poster.

In case you’re not familiar with Splice, it concerns “superstar genetic engineers Clive (Adrien Brody) and Elsa (Sarah Polley) specialize in splicing DNA from different animals to create incredible hybrids.” These driven scientists use human DNA to create a hybrid that, at first, surpasses their wildest dreams.

But as this hybrid, called Dren, begins to grow, those dreams turn into nightmare as it begins to develop unexpected abilities and appetites. Well, that does sound scary and after looking at this latest clip, I’m even more interested in this film. The effects look pretty good for such a low budget and who doesn’t love science gone wrong allegories? I know I do.

We’ll bring you more on this film as it gets closer to the release date, including an exclusive interview with director Vincenzo Natali, so be sure and check back soon. Until then, check out the clip and poster after the jump. Splice hits theaters on June 4.

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This week on The Flickcast Chris, Matt and Christina talk about a whole bunch of new topics including the Disney/Marvel deal, Rob Zombie making a new Blob movie, Star Wars comics on the iPhone, the remake of the classic film Heathers as a TV show, Summer Glau heading to the Dollhouse, Apple’s latest OS Snow Leopard, Avatar tickets already on sale and much, much more.

The team also made some great picks again this week including Christina’s pick of The Simpsons Season 12, Matt’s pick of the sci-fi thriller Cube and Chris’ pick of Dollhouse Season One.

As always, if you have comments, questions, critiques or offers of sponsorship, feel free to hit us up in the comments, on Twitter and at Facebook, MySpace or via email.

Thanks for listening.

For those who didn’t have the opportunity to come down to San Diego Comic-Con, here are some pics from my own photo journal of the event. Everything from Star Wars costumes, Street Fighter characters, gigantic booth displays and even everyone’s favorite Lou Ferrigno, it’s all here.

Enjoy. For our other photos from the Con, go here, here and here. Check out all of John’s photos after the jump.

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