Jeff is a jobless 30-year-old slacker man-child who does indeed live in the basement of his mother’s house. He is an expert at marijuana smoke rings, daytime television and pickup basketball but whines and protests when asked to perform a simple household errand for his mother (a wonderful Susan Sarandon). Lost and paralyzed, he casts desperately about for clues on what to do with his life, as per a favorite movie, 2002′s Signs, M. Night Shamalayan’s ridiculously self-serious examination of the eerie and paranormal.

So far the title character sounds like a cliché of the zeitgeist, but as played by the shambolically charming Jason Segel, and in the witty, expertly paced hands of the Duplass brothers, this movie is joyful entertainment from start to finish. Jeff is earnest and open-hearted. When the universe sends a sign, he follows. Never mind that every step ends in folly and humiliation. It is enough for him that there is a path.

That path merges him directly into the way of his distant, scornful brother, Pat (Ed Helms, channeling a lower-runged, far angrier version of his uptight corporate drone in The Office). Pat is an underling who has to spend his days in a hideous paint company shirt and tie, lives in a low-end apartment complex with his sweet and pretty wife (Judy Greer) and is suffering an early midlife crisis manifested by the purchase of a Porsche he can’t even begin to pay off, but hey, at least he has a job.

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I got a chance to sit down for a round table discussion with Jonah Hill and John C. Reilly, two of the stars of Cyrus, which premiered at the 2010 SXSW festival. Hill plays Cyrus, a 21 year old living with his mother (Catherine Keener) who develops an antagonistic and competitive relationship with his mom’s boyfriend played by Reilly.

So do you think the John C. Reilly era of a romantic lead in a comedy is finally here?

John C. Reilly: I hope so. I’m a very romantic type person. I like doing parts like this, and I think that there are a lot of people out there who are not represented in movies, whose stories don’t get told.

You know what I’m talking about (to a male journalist.) Neither of us look like Brad Pitt, let’s not fool ourselves.

Your characters had some similarities and some differences, you both have a co-dependence thing, did that come into play when you preparing as far as how your characters related to each other?

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